Serum Midkine Levels in Systemic Lupus Erythematosus

Neurobrucellosis in systemic lupus erythematosus

Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...

Increased Serum Levels of Soluble B7-H4 in Patients with Systemic Lupus Erythematosus

Serum interferon levels in patients with systemic lupus erythematosus.

Levels of interferon (IFN) were measured in 81 serum samples from 23 patients with systemic lupus erythematosus (SLE) by a plaque-reduction method and correlated retrospectively with clinical records of disease activity, anti-DNA binding, and serum complement measurements. IFN titers were found to correlate with both clinical disease activity and anti-DNA binding, but no relation was found to s...

Elevated plasma midkine and pleiotrophin levels in patients with systemic lupus erythematosus

Emerging evidence suggests that two heparin-binding growth factor, midkine and pleiotrophin are implicated in the pathogenesis of autoimmune diseases including SLE. To investigate the plasma midkine and pleiotrophin levels in SLE patients, as well as their correlation with major clinical parameters and interleukin-17 (IL-17) level in SLE, 83 SLE patients and 123 controls including 20 rheumatoid...

Systemic Lupus Erythematosus activity and serum bilirubins.

BACKGROUND Serum bilirubins play an important role in controlling oxidative stress; there is increased oxidative stress during activity of rheumatic diseases such as systemic lupus erythematosus (SLE). OBJECTIVE To study bilirubin levels in SLE (Systemic Lupus Erythematosus) patients and relate them to disease activity. METHODS We analyzed levels of total bilirubins (TB), direct bilirubins ...